Living with NMOSD
Factors influencing their well-being negatively include pain, inability to work and reduced sexual function.1 Also dissatisfaction with treatment options and economic burden correlate with their quality of life (QoL).1
* A retrospective study of a US administrative claims database (n = 1349). Data presented here are from patients with highly active NMOSD (n=134) with at least two relapses in the 12 months following the index date.2
< 70%

* Cross-sectional survey design study was conducted using validated instruments to assess physical, emotional, and socioeconomic burden of NMOSD on QoL among 193 patients.1

n = 100/193.1
* Assessment of physical, emotional, and socioeconomic burden of NMOSD on QoL among 193 patients.1
Each determinant represents the mean on a scale of 1–5, 1–6, or 1–10. The higher the mean score on the scale, the more the patient perceived NMOSD has impacted that particular aspect of their life.1

28% of patients living with NMOSD report experiencing moderate–to–severe depression.*6

* Based on an observational study of 71 patients diagnosed with NMOSD.6
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NMOSD, neuromyelitis optica spectrum disorder; QoL, quality of life.
Beekman J, et al. Neuromyelitis optica spectrum disorder: Patient experience and quality of life. Neurol Neuroimmunol Neuroinflamm. 2019;6(4):e580. Ajmera MR, et al. Evaluation of comorbidities and health care resource use among patients with highly active neuromyelitis optica. J Neurol Sci. 2018;384:96–103. Jarius S, et al. Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients. J. Neuroinflammation. 2012;9(1):14. Brod SA. Review of approved NMO therapies based on mechanism of action, efficacy and long-term effects. Mult Scler Relat Disord. 2020;46:102538. Jasiak–Zatonska M, et al. The immunology of neuromyelitis optica- Current knowledge, clinical implications, controversies and future implications. Int J Mol Sci. 2016;17(3):273. Chavarro VS, et al. Insufficient treatment of severe depression in neuromyelitis optica spectrum disorder. Neurol Neuroimmunol Neuroinflamm. 2016;3:e286.
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